surviving sepsis campaign 2016

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Red Cell Distribution Width As a Predictor of Mortality in Patients With Sepsis. Unable to load your collection due to an error, Unable to load your delegates due to an error. 2016 Feb 23;315(8):762-74 Pediatr Crit Care Med. 3- Recomiendan que tras la resucitación inicial se administren líquidos adicionales, gui窶ｦ The purpose of the SSC is to create an international collaborative effort to improve the treatment of sepsis and reduce the high mortality rate associated with the condition. Workman JK, Ames SG, Reeder RW, Korgenski EK, Masotti SM, Bratton SL, Larsen GY. eCollection 2020. In 2002, the Surviving Sepsis Campaign was formed as a partnership between the Society of Critical Campaña para sobrevivir a la sepsis: recomendaciones internacionales para el tratamiento de la sepsis y el choque septicémico: 2016 Andrew Rhodes, MB BS, MD(Res) (Co-chair)1; Laura E. Evans, MD, MSc, FCCM (Co-chair)23 Cent Eur J Immunol. Journal Club Surviving Sepsis Campaign Guideline 2016. Despite tremendous research efforts, several recommendations in the new sepsis guideline have a weak to moderate evidence grade. 2016 Oct;17(10):e451-e458. Crit Care Med. A bedside practitioner responsible for immediate decision making and trusting guidelines process will focus on the recommendations. eCollection 2020. Nominal groups were assembled at key international meetings (for those committee members attending the conference). Intensive Care Med. Several issues, such as the effect of the Sepsis-3 definition on the early recognition of sepsis, the selection of appropriate fluid and antibiotic therapy, as well as individualizing sepsis management are yet to be addressed. This site needs JavaScript to work properly. Bethesda, MD 20894, Copyright COVID-19 is an emerging, rapidly evolving situation. 2021 Feb 24;3(3):e0344. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Crit Care Med . 2021 Jan 25;13(1):e12912. 閭梧勹. Epub 2013 Jan 30. Accessibility Surviving Sepsis Campaign International Guidelines for the Management of Septic Shock and Sepsis-Associated Organ Dysfunction in Children. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af. This new guideline came at the beginning of the paradigm shift in sepsis definition, whereby the influence of the current sepsis definition on the management of sepsis 窶ｦ Caspase-1-Dependent Pyroptosis of Peripheral Blood Mononuclear Cells Is Associated with the Severity and Mortality of Septic Patients. Prevention and treatment information (HHS). -, J Crit Care. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. R35 GM119519/GM/NIGMS NIH HHS/United States. Epub 2017 Jan 18. The Surviving Sepsis Campaign (SSC) (survivingsepsis.org), has released its 2016 guidelines for the management of sepsis and septic shock.The document, published simultaneously in Critical Care Medicine and Intensive Care Medicine, is an update to the 2012 SSC guidelines. doi: 10.1097/CCE.0000000000000344. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R et al. 8600 Rockville Pike This group of users may find the tables of abbreviated recommendations竏稚he essence of the guidelines condensed to 7 pages竏弾specially useful. The 2016 Surviving Sepsis Campaign sepsis guideline presents current evidence and consequences in the management of sepsis. The Presentation, Pace, and Profile of Infection and Sepsis Patients Hospitalized Through the Emergency Department: An Exploratory Analysis. Would you like email updates of new search results? SURVIVING SEPSIS CAMPAIGN GUIDELINES 2016 Home > Linee guida > SURVIVING SEPSIS CAMPAIGN GUIDELINES 2016 Le linee guida di Surviving Sepsis Campaign (SSC) sono le più complete a disposizione per la gestione del paziente settico e in shock settico; costituite da SCCM ed ESICM, sono recepite da più di 30 società scientifiche. Would you like email updates of new search results? A person with sepsis is more likely to die from sepsis than a person who suffers a heart attack, stroke, or other major trauma. Reviewed and revised 8 January 2016 OVERVIEW The Surviving Sepsis Campaign (SSC) is a joint collaboration of the Society of Critical Care Medicine and the European Society of Intensive Care Medicine that seeks to reduce mortality from severe sepsis and septic shock worldwide. 2017 Mar;43(3):304-377. doi: 10.1007/s00134-017-4683-6. The outer layer represents the recommendations. 44, No. Intensive Care Med. COVID-19 is an emerging, rapidly evolving situation. Surviving Sepsis Campaign (SSC) sepsis bundles is associated with improved outcomes. En 2016 se publicó Association between disease-related malnutrition and innate immunity gene expression in critically ill patients at intensive care unit admission. Although a significant number of aspects of care have relatively weak support, evidence-based recommendations regarding the acute management of sepsis and septic shock are the foundation of improved outcomes for these critically ill patients with high mortality. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb SA, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including the Pediatric Subgroup. eCollection 2021 Mar. The definitions of sepsis and septic shock have undergone evolution over the past 15 years, and different documents continue to use different versions of the definitions, which can lead to confusion [ 3窶�9 ]. 2020 Jun 16;172(12):JC62. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 2020 Feb;46(Suppl 1):10-67. doi: 10.1007/s00134-019-05878-6. Intensive Care Med. Surviving Sepsis Campaign guidelines (SSCG)縺ｯcritical care 鬆伜沺縺ｧ譛�繧よｳｨ逶ｮ繧帝寔繧��ｼ後∪縺滓怙繧る�ｻ郢√↓閾ｨ蠎雁ｿ懃畑縺輔ｌ縺ｦ縺�繧九ぎ繧､繝峨Λ繧､繝ｳ縺ｧ縺ゅｋ縲� 2004 蟷ｴ縺ｫ蛻晉沿[1]縺鯉ｼ御ｺ� Surviving Sepsis Campaign International Guidelines for Management of Sepsis and Septic shock: 2016 New Definitions (Sepsis 3) Sepsis : life-threatening organ dysfunction caused by a dysregulated host response to infection. doi: 10.7759/cureus.12912. Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. Intensive Care Med. 2017 Mar;45(3):486-552. doi: 10.1097/CCM.0000000000002255. FOIA 2 www.tnpj.com 30 mL/kg should be given within the �ｬ� rst 3 hours of presentation (strong Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes 1* , Laura E. Evans 2 , Waleed Alhazzani 3 , Mitchell M. Levy 4 , Massimo Antonelli 5 , Ricard Ferrer 6 , Anand Kumar 7 , Jonathan E. Sevransky 8 , Charles L. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock Evidence-based updates to the 2016 Surviving Sepsis Guidelines and clinical implications 28 The Nurse Practitioner 窶� Vol. Epub 2017 Jan 18. Liu VX, Bhimarao M, Greene JD, Manickam RN, Martinez A, Schuler A, Barreda F, Escobar GJ. 2017 Mar;45(3):486-552. doi: 10.1097/CCM.0000000000002255. Privacy, Help Teleconferences and electronic-based discussion among subgroups and among the entire committee served as an integral part of the development. doi: 10.7326/ACPJ202006160-062. Markus Castegren, funktionsområdeschef för intensivvård på Karolinska Huddinge och Solna, föreläser om "Surviving sepsis campaign窶ｦ Surviving sepsis campaign 2016 on Vimeo Join Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock, 2012. Crit Care Med. 2- Recomiendan que en la resucitación de la hipoperfusión inducida por Sepsis, se administren al menos 30 cc/kg iv de cristaloides, dentro de las tres primeras horas (recomendación fuerte, calidad de la evidencia baja). 窶｢ The Surviving Sepsis Campaign (SSC) - global initiative to bring together professional organizations in reducing mortality from sepsis. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Bethesda, MD 20894, Copyright A stand-alone meeting was held for all panel members in December 2015. The next layer represents the rationales for the recommendations, illuminating the logic窶杯he evi窶ｦ Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP. Recently, the Surviving Sepsis Campaign released their 2016 guideline update. Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008. doi: 10.1097/PCC.0000000000000906. 窶｢ The Surviving Sepsis Guidelines縺ｯ2004蟷ｴ縺ｫ逋ｺ陦ｨ縲� 2008蟷ｴ縺ｨ2012蟷ｴ縺ｫ謾ｹ螳�. 2014 Oct 9;371(15):1381-91 Methods: 縺励°縺暦ｼ郡urviving Sepsis Campaign Guideline 2016縺ｧ縺ｯ�ｼ後％縺ｮ莉句�･譁ｹ豕輔↓繧医ｋ譛牙ｮｳ莠玖ｱ｡縺ｯ蝣ｱ蜻翫＆繧後※縺�縺ｪ縺�縺薙→縺九ｉ�ｼ御ｻ･蜑阪�ｮ逶ｮ讓吝�､繧堤畑縺�繧九％縺ｨ縺ｯ縺�縺ｾ縺�螳牙�ｨ縺ｧ縺ゅｋ縺ｨ縺励※縺�繧� 7�ｼ峨�ゅ＆繧峨↓�ｼ軍ivers繧峨�ｮ蝣ｱ蜻翫�ｯ�ｼ梧風陦�逞�險ｺ逋ゅ↓縺翫＞縺ｦ縲梧掠譛� Anti-infective agents; Fluid therapy; Hemodynamics; Lactate; Shock, septic. Am J Emerg Med. National Library of Medicine Surviving sepsis campaign: international guidelines for management of severe sepsis and septic shock: 2012. 2021 Mar 6;12(1):164. doi: 10.1186/s13287-021-02218-8. 2021 Feb 15;7:616694. doi: 10.3389/fmed.2020.616694. The Surviving Sepsis Campaign (SSC) is a joint collaboration of the Society of Critical Care Medicine (SCCM) and the European Society of Intensive Care Medicine (ESICM) committed to reducing mortality and morbidity from sepsis and septic shock worldwide. Front Med (Lausanne). Treatment of Pediatric Septic Shock With the Surviving Sepsis Campaign Guidelines and PICU Patient Outcomes. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes, MB BS, MD(Res) (Co-chair) 1; Laura E. Evans, MD, MSc, FCCM (Co-chair) 2; Waleed Alhazzani, MD 3 4; This site needs JavaScript to work properly. -, JAMA. -, Intensive Care Med. -. Results: 2020;45(4):414-424. doi: 10.5114/ceji.2020.103393. 1). The Surviving Sepsis Campaign Guidelines do not differentiate between patients with suspected sepsis and suspected septic shock. 2017 Mar 1;45(3):486-552. The Surviving Sepsis Campaign, an initiative of the Society of Critical Care Medicine, the European Society of Intensive Care Medicine and the International Sepsis Forum, has released the 2016 Surviving Sepsis Campaign (SSC) guidelines for the management of severe sepsis and septic shock. SSC produce guidelines that have been endorsed by many professional organizations throughout the world 窶ｦ Słotwiński R, Dąbrowska A, Kosałka K, Kański A, Słotwińska SM. Ann Intern Med. 窶｢ 4迚育岼繧�2017蟷ｴ1譛医�ｮSCCM 窶ｦ Please enable it to take advantage of the complete set of features! MSCs derived from amniotic fluid and umbilical cord require different administration schemes and exert different curative effects on different tissues in rats with CLP-induced sepsis. Appendix 2. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Please enable it to take advantage of the complete set of features! Chen R, Xie Y, Zhong X, Chen F, Gong Y, Wang N, Wang D. Stem Cell Res Ther. Clipboard, Search History, and several other advanced features are temporarily unavailable. 2016 Jul 14;375(2):122-33 In a single-center U.S. study, investigators described a severe sepsis and septic shock mortality reduction to less than 10% with improved Kim B, Kim K, Lee J, Kim J, Jo YH, Lee JH, Hwang JE. Privacy, Help 2020 Feb 28;2020:9152140. doi: 10.1155/2020/9152140. The panel consisted of five sections: hemodynamics, infection, adjunctive therapies, metabolic, and ventilation. 2017 Mar;43(3):304-377. doi: 10.1007/s00134-017-4683-6. doi: 10.1097/PCC.0000000000002198. The 2016 Surviving Sepsis Campaign sepsis guideline presents current evidence and consequences in the management of sepsis. Weiss SL, Peters MJ, Alhazzani W, Agus MSD, Flori HR, Inwald DP, Nadel S, Schlapbach LJ, Tasker RC, Argent AC, Brierley J, Carcillo J, Carrol ED, Carroll CL, Cheifetz IM, Choong K, Cies JJ, Cruz AT, De Luca D, Deep A, Faust SN, De Oliveira CF, Hall MW, Ishimine P, Javouhey E, Joosten KFM, Joshi P, Karam O, Kneyber MCJ, Lemson J, MacLaren G, Mehta NM, Møller MH, Newth CJL, Nguyen TC, Nishisaki A, Nunnally ME, Parker MM, Paul RM, Randolph AG, Ranjit S, Romer LH, Scott HF, Tume LN, Verger JT, Williams EA, Wolf J, Wong HR, Zimmerman JJ, Kissoon N, Tissieres P. Pediatr Crit Care Med. 2013 Feb;39(2):165-228 Objective To provide an update to 窶彜urviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012窶�. 2020 Feb;21(2):e52-e106. Prevention and treatment information (HHS), Objective: With these musings, I turn to the new 2016 Surviving Sepsis Guidelines; and you窶决e in luck because I窶况e just brewed a warm bowl of cheese dip. Keywords: Fenner BP, Darden DB, Kelly LS, Rincon J, Brakenridge SC, Larson SD, Moore FA, Efron PA, Moldawer LL. The Surviving Sepsis Guideline panel provided 93 statements on early management and resuscitation of patients with sepsis or septic shock. 窶｢ 2002蟷ｴThe Surviving Sepsis Campaign (SSC) 竊�29470莠ｺ縺ｮ隕ｳ蟇溽�皮ｩｶ縺ｧ縺ｯ豁ｻ莠｡邇�貂� �ｼ�odds ratio, 0.96; 95%%CI, 0.95-97; p < .001�ｼ�. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 INTENSIVE CARE MEDICINE ESICM is pleased to present the 2016 edition of the Surviving Sepsis Campaign窶冱 (SSC) practice guidelines in our official journal Intensive Care Medicine. 2013 Feb;41(2):580-637. doi: 10.1097/CCM.0b013e31827e83af. The guidelines may be thought of as several concentric layers, similar to an onion (Fig. Each subgroup generated a list of questions, searched for best available evidence, and then followed the principles of the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) system to assess the quality of evidence from high to very low, and to formulate recommendations as strong or weak, or best practice statement when applicable. Recomendaciones 2016 1- Sepsis y shock séptico son emergencias médicas y estas nuevas Guías recomiendan que el tratamiento y la resucitación comiencen inmediatamente (窶彙est practice statements窶� BPS). Currently, there is a discussion underway amongst a number of experts with regards to this bundle. No recommendation was provided for four questions. Rhodes A, Evans LE, Alhazzani W, Levy MM, Antonelli M, Ferrer R, Kumar A, Sevransky JE, Sprung CL, Nunnally ME, Rochwerg B, Rubenfeld GD, Angus DC, Annane D, Beale RJ, Bellinghan GJ, Bernard GR, Chiche JD, Coopersmith C, De Backer DP, French CJ, Fujishima S, Gerlach H, Hidalgo JL, Hollenberg SM, Jones AE, Karnad DR, Kleinpell RM, Koh Y, Lisboa TC, Machado FR, Marini JJ, Marshall JC, Mazuski JE, McIntyre LA, McLean AS, Mehta S, Moreno RP, Myburgh J, Navalesi P, Nishida O, Osborn TM, Perner A, Plunkett CM, Ranieri M, Schorr CA, Seckel MA, Seymour CW, Shieh L, Shukri KA, Simpson SQ, Singer M, Thompson BT, Townsend SR, Van der Poll T, Vincent JL, Wiersinga WJ, Zimmerman JL, Dellinger RP. Crit Care Med. Surviving sepsis campaign international guidelines for the management of septic shock and sepsis-associated organ dysfunction in children. 2013 Feb;39(2):165-228. doi: 10.1007/s00134-012-2769-8. Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, Sevransky JE, Sprung CL, Douglas IS, Jaeschke R, Osborn TM, Nunnally ME, Townsend SR, Reinhart K, Kleinpell RM, Angus DC, Deutschman CS, Machado FR, Rubenfeld GD, Webb S, Beale RJ, Vincent JL, Moreno R; Surviving Sepsis Campaign Guidelines Committee including The Pediatric Subgroup. Unable to load your collection due to an error, Unable to load your delegates due to an error. 2008 Jan;36(1):296-327. doi: 10.1097/01.CCM.0000298158.12101.41. Wang Y, Liu Y, Liu Q, Zheng Q, Dong X, Liu X, Gao W, Bai X, Li Z. Biomed Res Int. Conclusions: Immunological Endotyping of Chronic Critical Illness After Severe Sepsis. Therefore, the current guideline is also a call for the intensive care community for more and better research on sepsis treatment. -, N Engl J Med. Overall, 32 were strong recommendations, 39 were weak recommendations, and 18 were best-practice statements. N Engl J Med. Crit Care Med 2017; 3:00窶�00. Clipboard, Search History, and several other advanced features are temporarily unavailable. Sepsis is still associated with very high morbidity and mortality. FOIA A consensus committee of 55 international experts representing 25 international organizations was convened. Best practice statements and recommendations for caring for critically ill patients with COVID-19. Careers. Krishna V, Pillai G, Velickakathu Sukumaran S. Cureus. Overall, I think this iteration moves the guidelines closer to the best evidence out there. Crit Care Med. Epub 2021 Jan 30. Design: 2018 May;36(5):758-762. doi: 10.1016/j.ajem.2017.10.005. A formal conflict-of-interest (COI) policy was developed at the onset of the process and enforced throughout. Accessibility Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes1*, Laura E. Evans2, Waleed Alhazzani 3, Mitchell M. Levy4, Massimo Antonelli5, Ricard Ferrer6, 78923, Of course, when you travel that path it forces a divergence from Comparison of Recommendations from 2012 to 2016 PURPOSE To provide an update to the Surviving Sepsis Campaign guidelines for Management of Sepsis 窶ｦ Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes, MB BS, MD(Res) (Co-chair) 1; Laura E. Evans, MD, MSc, FCCM (Co-chair) 2; Waleed Alhazzani, MD 3 4; Impact of bacteremia prediction rule in CAP: Before and after study. Substantial agreement exists among a large cohort of international experts regarding many strong recommendations for the best care of patients with sepsis. Careers. This new guideline came at the beginning of the paradigm shift in sepsis definition, whereby the influence of the current sepsis definition on the management of sepsis is yet to be seen. Of note, however, is that most of the world's population resides in low-income and middle-income countries (LMICs), where the burden of sepsis is enormous, outcomes are often poor, and socioeconomic 窶ｦ 2017/02/14 譚ｱ莠ｬ繝吶う繝ｻ豬ｦ螳牙ｸょｷ晏現逋ゅそ繝ｳ繧ｿ繝ｼ謨第�･髮�荳ｭ豐ｻ逋らｧ� 譛蛾�� 閨｡. Population, intervention, comparison, and outcomes (PICO) questions were reviewed and updated as needed, and evidence profiles were generated. Crit Care Explor. Critical care medicine . Dellinger RP, Levy MM, Carlet JM, Bion J, Parker MM, Jaeschke R, Reinhart K, Angus DC, Brun-Buisson C, Beale R, Calandra T, Dhainaut JF, Gerlach H, Harvey M, Marini JJ, Marshall J, Ranieri M, Ramsay G, Sevransky J, Thompson BT, Townsend S, Vender JS, Zimmerman JL, Vincent JL; International Surviving Sepsis Campaign Guidelines Committee; American Association of Critical-Care Nurses; American College of Chest Physicians; American College of Emergency Physicians; Canadian Critical Care Society; European Society of Clinical Microbiology and Infectious Diseases; European Society of Intensive Care Medicine; European Respiratory Society; International Sepsis Forum; Japanese Association for Acute Medicine; Japanese Society of Intensive Care Medicine; Society of Critical Care Medicine; Society of Hospital Medicine; Surgical Infection Society; World Federation of Societies of Intensive and Critical Care Medicine. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016. Epub 2017 Oct 4. 2016 Oct;35:75-83 8600 Rockville Pike In the most recent international Surviving Sepsis Campaign guidelines, Rhodes and colleagues1 excellently outline evidence-based management of patients with sepsis and septic shock. National Library of Medicine To provide an update to "Surviving Sepsis Campaign Guidelines for Management of Sepsis and Septic Shock: 2012.". New Definition Firstly, there is the new definition of sepsis , as described here previously. SURVIVING SEPSIS CAMPAIGN 2016 Fernández Quero L. Hospital General Universitario Gregorio Marañón 窶� Madrid Resumen En los últimos meses el paisaje de la sepsis ha cambiado substancialmente. Surviving Sepsis Campaign: International Guidelines for Management of Sepsis and Septic Shock: 2016 Andrew Rhodes 1, 窶｢ The Surviving Sepsis Campaign and the Institute for Healthcare Improvement teamed up to 19. The Surviving Sepsis Campaign (SSC) is a global initiative to bring together professional organizations in reducing mortality from sepsis. The Surviving Sepsis Campaign Bundle: 2018 update The Surviving Sepsis Campaign (SSC) has released a new updated Hour-1 Bundle to reflect the latest evidence from the International Guidelines for Management of Sepsis and Septic Shock 2016. Continuous improvements in the early recognition and management of this syndrome are thus necessary.

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